In this document, reference to asf or csf is intended to refer to the specific disease. Classical swine fever csf, hog cholera, european swine fever is caused by species classical swine fever virus csfv, an enveloped singlestranded rna virus of positive polarity in the family flaviviridae, genus pestivirus. General provisions for the purposes of international trade, classical swine fever csf is defined as an infection of domestic pigs. Classical swine fever hog cholera iowa state university. Classical swine fever csf occurs only in swine, and all age groups are susceptible.
Basic measures to control epidemics of csf comprise eradication of infected herds and preventive emptying of herds at risk. General provisions for the purposes of international trade, classical swine fever csf is. Efficient live attenuated vaccines against classical swine fever virus csfv are used. Demam babi classical swine fever protokol veterinar malaysia bagi penyakit demam babi classical swine fever csf ini merupakan panduan rasmi kepada anggota jabatan perkhidmatan. Aug 10, 2017 classical swine fever csf is a contagious febrile disease of pigs that is associated with high lethality.
Pdf classical swine fever csf is of increasing concern in europe where wild boar appear to play an important epidemiological role. It is shown here that the end stage of lethal infection in the natural. Classical swine fever csf, hog cholera, swine fever, european swine fever. Classical importance swine fever hog cholera, swine fever, european swine fever, peste du porc, colera porcina, virusschweinepest last updated. Aug 26, 2014 if classical swine fever is confirmed it will be controlled in line with the contingency plan for exotic notifiable diseases and the gb classical swine fever disease control strategy. The red book 2012 as well as updates to other current foreign animal. Classical swine fever virus csfv, the causative agent of csf, is a member of the genus pestivirus, which belongs to the flaviviridae family. It was first described in the early 19th century in the usa. Comparison of six rna extraction methods for the detection of. Epidemiology, diagnosis and control of classical swine.
Sep 12, 2018 preliminary outbreak assessment and updated situation assessments for classical swine fever in japan. The disease is similar to classical swine fever, but is caused by a different virus. In recent years, numerous studies related to the immune escape mechanism of the persistent infection and pathogenesis of csfv have been performed. Classical swine fever definition of classical swine fever. Although several countries have become free from classical swine fever after eradication programs, sporadic outbreaks continue to occur in most major pigproducing countries, and classical swine fever is endemic to some countries in asia.
In countries which are free of disease, or where eradication is in progress, vaccination is normally prohibited. Infection occurs in wild and domestic pigs, including wild. Classical swine fever an overview sciencedirect topics. Pdf reemergence of classical swine fever, japan, 2018. Natural hosts for the csf virus csfv are members of the family suidae, i. Dynamics of classical swine fever spread in wild boar in. Classical swine fever csf causes major losses in pig farming, with various degrees of disease severity. Csf in wild boar poses a serious threat to domestic pigs. However, it is impossible to serologically differentiate mlv vaccinated pigs from those infected with csf virus csfv. The individual outcome depends on the age of the infected animal and the viru. Classical swine fever csf or hog cholera is a highly contagious swine viral disease. Classical swine fever csf virus is a member of the family flaviviridae, genus pestivirus, containing one serotype divided into three major genotypes, including. The prolongation of the classic swine fever csf outbreak in. Overview of classical swine fever generalized conditions.
Classical swine fever outbreak after modified live lom strain. Classification of the causative agent resistance to. Classic swine fever, ars discoveries are providing vital information to help fight this economically devastating disease, which affects cattle and other clovenhoofed animals. In the united states, csf was once a frequent occurrence but was eradicated in 1976. Classical swine fever is a notifiable disease, according to council directive 82894eec of 21 december 1982 on the notification of animal diseases within the community. Classical swine fever csf, also known as hog chol era, is a highly contagious viral disease of swine. If classical swine fever is confirmed it will be controlled in line with the contingency plan for exotic notifiable diseases and the gb classical swine fever disease control strategy. The classical swine fever eradication plan for the americas 1 1. Characteristic signs of the disease, such as fever and bleeding under the skin, can resemble other diseases, making it important to accurately diagnose. Classical swine fever csf is a severe acute infectious disease that results from classical swine fever virus csfv infection, which leads to serious economic losses in the porcine industry worldwide. Csf was eradicated from the united states in 1978 after. The supposed first record of a disease in pigs corresponding to what we now know as classical swine fever. The disease occurs in most major swine raising countries where eradication programs have not been successfully implemented.
Classical swine fever csf or hog cholera also sometimes called pig plague based on the german word schweinepest is a highly contagious disease of swine old world and new world pigs. Classic swine fever, ars discoveries are providing vital information to help fight this economically devastating disease, which affects cattle and other cloven. We are advising the public that a risk analysis has been prepared by the animal plant health inspection service aphis relative to the risk of introducing classical swine fever virus in swine and swine. Efficient live attenuated vaccines against classical swine fever virus csfv are used routinely in endemic countries. To control the disease in either endemic situations or in case. Preliminary outbreak assessment and updated situation assessments for classical swine fever in japan. To determine the epidemiological characteristics of its spread, a spatiotemporal analysis was performed using actual field data on the current epidemic. Csf may go undiagnosed for months due to its mild nature and few lesions. Classical swine fever csf remains one of the most important transboundary viral diseases of swine worldwide. Csf endemic countries have to use routine vaccination with modified live virus mlv vaccines to prevent and control csf. Where it exists around the world, it affects only pigs and wild boars. Csf was eradicated from the united states in 1978 after a 16year effort by the industry and state and federal governments. Pigs immunized with a novel e2 subunit vaccine are protected.
It is shown here that the end stage of lethal infection in the natural host is associated with a dramatic depletion preferentially of b lymphocytes in the circulatory system as well as in lymphoid tissues. Classical swine fever csf is a highly contagious and often fatal disease of swine, affecting domestic and wild pig populations. Classical swine fever aetiology epidemiology diagnosis prevention and control references aetiology classification of the causative agent classical swine fever csf virus is a member of the family flaviviridae, genus pestivirus, containing one serotype divided into three major genotypes, including numerous subgenotypes. Oie standards for surveillance as applied have helped eradicate csf from north america and much of western europe. Demam babi classical swine fever protokol veterinar malaysia bagi penyakit demam babi classical swine fever csf ini merupakan panduan rasmi kepada anggota jabatan perkhidmatan veterinar jpv dalam mengawal dan membasmi penyakit tersebut. Where the collective term swine fever is used it is intended to refer to both asf and csf. In the us, classical swine fever aka hog cholera is considered a foreign animal disease. Usda aphis classical swine fever standard operating procedure. Pdf the principles of aetiology, pathogenesis, diagnosis and immunology of classical swine fever as well as control measures are described. The red book 2012 as well as updates to other current foreign animal disease preparedness and response plan fad prep materials.
The red book 20 incorporates comments received on the csf response plan. Besides high fever, the disease is characterized by a broad spectrum of clinical signs. Classical swine fever virus csfv is an enveloped singlestranded rna virus of positive polarity in the family flaviviridae, genus pestivirus. Veterinary services august 2008 classical swine fever still a threat classical swine fever csf, also known as hog cholera, is a highly contagious viral disease of swine. Csfv is an enveloped rna virus belonging to the pestivirus genus of the flaviviridae family. Classification of the causative agent resistance to physical. Classical swine fever virus csfv, the causative agent of csf, is a member.
Classical swine fever csf remains one of the most important viral diseases that affect sustainable pig production worldwide. Role of wild boar in the spread of classical swine fever in japan. Classical swine fever csf is a contagious febrile disease of pigs that is associated. Although several countries have become free from classical swine fever after eradication programs. Classical swine fever was first detected in the united states in the nineteenth century. Classical swine fever csf is a highly contagious and economically significant. Classical swine fever csf is one of the most important viral diseases of domestic pigs and wild boar. We are advising the public that a risk analysis has been prepared by the animal plant health inspection service aphis relative to the risk of introducing classical swine fever virus in swine and swine products imported from france and spain. Classical swine fever is a contagious, often fatal, disease of pigs clinically characterized by high body temperature, lethargy, yellowish diarrhea, vomiting, and a purple skin discoloration of the ears, lower abdomen, and legs. Classical swine fever csf, hog cholera, european swine fever is caused by species classical swine fever virus csfv, an enveloped singlestranded rna virus of positive polarity.
Infection occurs in wild and domestic pigs, including wild boar, and rarely in cattle. The individual outcome depends on the age of the infected animal and the virulence of the virus and can range from fatal to subclinical. Please refer to the animal disease notification system for a description of the notification system and the latest health situation table. A highly infectious, often fatal viral disease of swine, characterized by fever, loss of appetite, and diarrhea. Epidemiology, diagnosis and control of classical swine fever.
The aim of this study is to develop a onedose e2subunit vaccine. Frontiers the control of classical swine fever in wild boar. Classical swine fever eu position the eu supports the adoption of the modified chapter. Csfv causes serious losses in the pig industry since it is highly contagious and pathogenic, and can cause widespread deaths. This risk analysis is a supplement to a risk analysis.
Classical swine fever national invasive species information. English pdf spanish pdf classical swine fever powerpoint this presentation is designed to aid veterinarians in educating swine producers on csf, its transmission, clinical signs, and prevention measures. Csf is identified by the united states department of agriculture usda as a highconsequence foreign animal disease fad because it is one of the. Aug 28, 2019 in the us, classical swine fever aka hog cholera is considered a foreign animal disease. North america is also at risk for the reintroduction of classical classical swine fever csf is a highly contagious and economically significant viral disease of pigs. Classical swine fever is a highly contagious disease of pigs that tremendously affects the swine industry. Classical swine fever aetiology epidemiology diagnosis prevention and control references aetiology classification of the causative agent classical swine fever csf virus is a member of the.
Classical swine fever csf is a viral disease with severe economic consequences for domestic pigs. Enzootic classical swine fever causes severe direct economic losses, and substantial costs are required to maintain. Domestic pig is defined as all domesticated pigs, permanently captive or farmed free range, used for the. A decade of research into classical swine fever marker. It is a notifiable disease in most countries of the world. Classical swine fever csf, otherwise known as hog cholera hc or just swine fever, is a specific viral disease of pigs. Disease control strategy for african and classical swine. Classical swine fever csf, also known as hog cholera, is a contagious viral disease of domestic and wild swine.
Hog cholera, also known as classical or european swine fever, is caused by hog cholera virus, a member of the genus pestivirus. Classical swine fever hog cholera summary classical swine fever csf, also known as hog cholera, is a contagious viral disease of pigs, including wild boar. Viral strains of low to moderate virulence cause infections with a gradient of severity, some clinically inapparent. About classical swine fever csfv classical swine fever virus csfv, bovine viral diarrhoea virus bvdv, and border disease virus bdv are the 3 members of the genus pestivirus within the family. Csf inactivation in meat this document provides the current scientific knowledge of the level of persistence of the csf virus in a variety of meat products, including hams and sausages. Penyakit csf adalah satu penyakit yang disebabkan oleh jangkitan sejenis virus. Rapid detection of classical swine fever virus by a portable. Herdchek classical swine fever virus csfv antigen test kitserum creating a userdefined assay is an easy process of two tasksediting an xchek file to allow you to create an assay, and then creating. Vaccination with modified live virus strains is effective in preventing losses in countries where classical swine fever is enzootic, but is unlikely, on its own, to eliminate infection entirely. Comparison of six rna extraction methods for the detection. Pdf classical swine fever hog cholera in wild boar in europe. Classical swine fever csf is a contagious febrile disease of pigs that is associated with high lethality.
African swine fever asf is a highly contagious virus that causes an often fatal disease in pigs and wild boar. Since september 2018, nearly 900 notifications of classical swine fever csf have been reported in gifu prefecture japan affecting domestic pig and wild boar by the end of august 2019. From the task bar, choose start run, and then type i into the text box. Classical swine fever is a contagious, often fatal, disease of pigs clinically characterized by high body temperature, lethargy, yellowish diarrhea, vomiting, and a purple skin discoloration of the ears, lower. Herdchek classical swine fever virus csfv antigen test kitserum creating a userdefined assay is an easy process of two tasksediting an xchek file to allow you to create an assay, and then creating the assay within xchek. The classical swine fever eradication plan for the america. About classical swine fever csfv classical swine fever virus csfv, bovine viral diarrhoea virus bvdv, and border disease virus bdv are the 3 members of the genus pestivirus within the family flaviviridae. Classical swine fever aetiology epidemiology diagnosis prevention and control references aetiology classification of the causative agent classical swine fever csf virus is a member of the family flaviviridae, genus pestivirus, containing one. The causative agent is csf virus, a small, enveloped rna virus of the genus pestivirus. Classical swine fever is a highly contagious, viral disease of swine that in its most virulent form causes morbidity and mortality approaching 100%. Efficacy of a live attenuated vaccine in classical swine. There is only one serotype with minor antigenic variants.
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